Comparison the effect of Indomethacin and Diclofenac Sodium in reducing pain after surgical removal of mandibular third molar

Comparison the prophylactic effect of Indomethacin and Diclofenac Sodium in reducing pain after surgical removal of mandibular horizontal impacted third molar

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20221004056088N1

Enrollment

Registered

2022-10-15

Start date

2022-10-08

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain after surgical removal of mandibular horizontal impacted third molar.

Interventions

Intervention 1: Intervention group: Intervention group A will use indomethacin tablet painkiller as a pain prevention drug. Intervention 2: Intervention group: Intervention group B will use the painki

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Patients' satisfaction with participating in the study Patients' satisfaction with participating in the study mandibular horizontal impacted third molar Patients without gastrointestinal ulcer Not taking painkillers or other drugs for 24 hours before surgery Not having a history of addiction to drugs or painkillers Patients who are not pregnant or breastfeeding. Known insensitivity to common non-steroidal anti-inflammatories and analgesics No history of nasal polyps, bronchospasm or angioedema caused by non-steroidal anti-inflammatory drugs. People who are able to take medicine orally.

Exclusion criteria

Exclusion criteria: Dissatisfaction of patients to continue the study Those who have used ketorolac

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Pain 6 hours after surgery and pain 12 hours after surgery and pain 24 hours after surgery. Method of measurement: The level of pain expressed by patients after horizontal third molar surgery.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBabak Hasanalizadmazhar

Shahre-kord University of Medical Sciences

goooolnaz75@gmail.com.

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026