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Effect of aftingel ointment in healing of mouth ulcers

Comparison of the Effectiveness of local aftingel ointment and First generation oral cephalosporins in Improving lip mucosal traumatic ulcers(laceration) in patients older than 17 years old

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221004056086N1
Enrollment
100
Registered
2022-10-19
Start date
2022-10-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic wounds of the oral mucosa (laceration).

Interventions

Intervention 1: Control group: preparation of the patient and the doctor, local anesthesia and preferably nerve block of the involved area, cleansing by washing with normal saline and wound repair wit

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
17 Years to No maximum

Inclusion criteria

Inclusion criteria: Patient satisfaction to participate in the study Age older than 17 years Absence of underlying disease such as liver and kidney disease, Diabetes Mellitus, progressive neurologic disorders, GI disorders and coagulopathy and Wound healing disorders Not taking any antibiotics for any reason less than 24 hours from the onset of the ulcer Wounds without requirement to debridement and smaller than 5 cm without malnutrition Simple wound without nerve damage and fracture Not taking medicine with known interference in wound healing

Exclusion criteria

Exclusion criteria: Incomplete information about type of wound Patients who don't want to participate in this study at any time during the study Taking any antibiotics for any reason less than 24 hours from the onset of the ulcer Wounds that have been created for more than 12 hours Wounds larger than 5 cm

Design outcomes

Primary

MeasureTime frame
Wound length. Timepoint: On 0, 3 and 7th days of treatment. Method of measurement: graded ruler in centimeters.;Wound healing time. Timepoint: On 0, 3 and 7th days of treatment. Method of measurement: Based on the length of wound in centimeters until complete wound healing.;Patient satisfaction. Timepoint: On 0, 3 and 7th days of treatment. Method of measurement: Likert scale.;Pain. Timepoint: On 0, 3 and 7th days of treatment. Method of measurement: Visual analouge scale(VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Azizkhani

Esfahan University of Medical Sciences

azizkhani1980@gmail.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026