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Investigating and comparing the effects of jujube vaginal cream and clotrimazole cream on vaginal candidiasis infection

Investigating and comparing the effects of jujube vaginal cream and Clotrimazole cream on vaginal Candidiasis in women of reproductive age

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221002056076N1
Enrollment
74
Registered
2023-08-01
Start date
2023-08-23
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vaginal candidiasis. Candidiasis of vulva and vagina

Interventions

Intervention 1: For one week, treated with 3% jujube vaginal cream and 1% clotrimazole, one applicator every night. Intervention 2: Control group: treated with clotrimazole 1% vaginal cream, one appli

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 49 Years

Inclusion criteria

Inclusion criteria: Written consent to participate in the study Have minimum literacy Resident of Mashhad Married and age range 15-49 Absence, no use of special medicine in the last two weeks No allergy to clotrimazole and jujube No pregnancy or breastfeeding No use of IUD and hormonal contraceptive method No recurrent vulvovaginitis candidiasis No use of oral and topical antifungal (vaginal candidiasis treatment) At least a score of 3 from the total score of symptoms of vaginal candidiasis Bell (according to the questionnaire) Positive test answer from the candidate's point of view

Exclusion criteria

Exclusion criteria: Occurrence of pregnancy Forgetting medication more than once Allergy to given medication Use of other antifungals Monthly habit during the study period Intimacy without using condom Withdrawal from participation in the research by the research unit

Design outcomes

Primary

MeasureTime frame
Vaginal candidiasis. Timepoint: One week ± 24 hours. Method of measurement: Culture of vaginal secretions in the laboratory.

Secondary

MeasureTime frame
Itching. Timepoint: Before treatment, one week ± 24 hours after treatment. Method of measurement: Patient history.;Erythema. Timepoint: Before treatment, one week ± 24 hours after treatment. Method of measurement: Patient history.;Burning. Timepoint: Before treatment, one week ± 24 hours after treatment. Method of measurement: Patient history.;Dys paranoia. Timepoint: Before treatment, one week ± 24 hours after treatment. Method of measurement: Patient history.;The result of the culture of vaginal secretions. Timepoint: Before treatment, one week ± 24 hours after treatment. Method of measurement: Patient history.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShima Bahadri

Mashhad University of Medical Sciences

bahadoris928@mums.ac.ir+98 51 3859 1511

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026