pemphigus vulgaris oral lesions. Pemphigus vulgaris
Conditions
Interventions
Intervention 1: Intervention group: The drug used in this group is drop pilocarpine 4%, which is put in another container to avoid getting identified by the patients. Patients will be using the drug f
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Clinical and histopathological confirmation of pemphigus vulgaris Patients with resistant oral ulcers that have not been treated with systemic drugs or have relapsed after treatment Age between 20-70 Accessible mouth lesions(retromolar trigone)
Exclusion criteria
Exclusion criteria: oral lesions more than 2-3
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Size of oral lesions. Timepoint: Baseline visit, week 4 and week 8. Method of measurement: Measuring the size of lesions in photos by software, evaluation of patient satisfaction, oral lesion status and disease severity using VAS, ODSS and PDAI questionnaires. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pemphigus disease area index (PDAI). Timepoint: Baseline visit and week 8. Method of measurement: Pemphigus disease area index questionnaire (PDAI). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Zeinab aryanian
Tehran University of Medical Sciences
Outcome results
None listed