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Comparison of the efficacy of rosemary lotion and ketoconazole lotion in treatment of seborrheic dermatitis

Efficacy of rosemary extract lotion in the treatment of dandruff in seborrheic dermatitis in comparison with ketoconazole %2 lotion a double-blind clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20221001056063N1
Enrollment
42
Registered
2022-10-11
Start date
2022-10-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Scalp seborrheic dermatitis. Seborrheic dermatitis, unspecified

Interventions

Intervention 1: Intervention group: Rosemay lotion is applied twice daily on the scalp for two months. Intervention 2: Control group: Ketoconazole 2% lotion is applied twice daily on the scalp for two

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients 18-60 years old clinical diagnosis of scalp seborrheic dermatitis ASFS score > 10 DLQI index > 2

Exclusion criteria

Exclusion criteria: Severe seborrheic dermatitis in other areas Using antibiotics or immunomodulatory drugs since one month before beginning of the research Using any topical drugs that can affect seborrheic dermatitis since two weeks before beginning of the research Using any oral drugs that can affect seborrheic dermatitis since one month before beginning of the research Other scalp diseases Scalp surgery in the previous month Sensitivity to the research drugs Pregnancy Lactation

Design outcomes

Primary

MeasureTime frame
Adherent scalp flaking score ( ASFS score ). Timepoint: Before intervention and 1 and 2 months after starting intervention. Method of measurement: Adherent scalp flaking score ( ASFS score ) formula.

Secondary

MeasureTime frame
Pruritus severity. Timepoint: before intervention and 1 and 2 months after starting intervention. Method of measurement: ItchyQuant itch illustrated numerical rating scale.;Quality of life. Timepoint: before intervention and 2 months after starting intervention. Method of measurement: Dermatology Life Quality index questionnaire Persian version.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Sadat Sadati

Shiraz University of Medical Sciences

msadati63@yahoo.com+98 71 3484 6316

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026