The effect of esomeprazole on preeclampsia

The effect of esomeprazole on preeclampsia in pregnant women

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220928056050N1

Enrollment

120

Registered

2022-09-30

Start date

2022-10-23

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pre-eclampsia. Pre-eclampsia

Interventions

Intervention 1: Intervention group: For the intervention group, a 40 mg esomeprazole capsule is prescribed daily until the end of the 34th week of pregnancy. Intervention 2: Control group: For the con

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Preeclampsia diagnosis Gestational age between 26 to 32 weeks Absence of anomalies in the fetus Fetus weight between 500 to 1800 grams

Exclusion criteria

Exclusion criteria: Eclampsia Chronic blood pressure Pulmonary edema Cerebrovascular problems Heart failure HELLP syndrome The use of proton pump inhibitors Renal failure Diffuse intravascular coagulation Fetal distress Hypersensitivity to proton pump inhibitors

Design outcomes

Primary

Measure	Time frame
Prolongation of gestation. Timepoint: Before intervention until delivery. Method of measurement: Using the patient medical record.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNilofar Azarbayejani

Sanandaj University of Medical Sciences

Dr.azarbayejani1990@gmail.com+98 87 3328 5910

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026