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Effect of microneedling and topical basic fibroblast growth factor in treatment of stretch marks

Comparison of the effect of combination microneedling and topical basic fibroblast growth factor with microneedling alone in the improvement of stria distensae

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220924056033N1
Enrollment
30
Registered
2022-10-07
Start date
2022-10-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stria distensa. Striae atrophicae

Interventions

Intervention 1: Intervention group: Combination of microneedling and Basic Fibroblas Growth Factor (BFGF) in the treatment of stria distensae (each month three sessions). Intervention 2: Control group

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patents between 18 and 60 years old

Exclusion criteria

Exclusion criteria: Pregnant women Lactating women Diabetic Hypertension Hypothyroidism Hyperthyroidism Immunosuppressed patients Patients who recieved stria treatment 3 months ago or have infection on the stria

Design outcomes

Primary

MeasureTime frame
Clinical improvement stria. Timepoint: Patients will be visited 4 times, 0, 1, 2, 5 month. Method of measurement: The GAIS(Global Aesthetic Improvement Scale) is measured as follows:Grade 0: worsening of lesions Grade1: No change (< 25% improvement)Grade 2: Improved (25-50% improvement)Grade 3: Much improved (51-75% improvement)Grade 4: Very much improved (76-100% improvement).

Secondary

MeasureTime frame
Stria size reduction. Timepoint: Patients will be visited 4 times, 0, 1, 2, 5 month. Method of measurement: Rate of width reduction (%)=Baseline width-Follow upwidth/Baseline width ×100.;Stria color. Timepoint: Patients will be visited 4 times, 0, 1, 2, 5 month. Method of measurement: Melanin index is measured bySkinColorCatch colorimeter(Delphin, Finland) and is presentedas average of .3 points measure.;Patient satisfaction. Timepoint: Patients will be visited 4 times, 0, 1, 2, 5 month. Method of measurement: Patient satisfaction is assessed by a 5point scale: 4: Extremely satisfied3: Very satisfied 2: satisfied 1:Slightly satisfied 0: Not satisfied.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRahil Hamedpour

Shiraz University of Medical Sciences

anisa1370@gmail.com+98 71 3234 4997

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026