Condition 1: Contrast-induced nephropathy. Condition 2: chronic kidney disease. Nephropathy induced by other drugs, medicaments and biological substances Chronic kidney disease, unspecified
Conditions
Interventions
Intervention 1: Control group: this group will receive standard and routine treatment in such a way that ACE, ARB, metformin and NSAID drugs will stopped and NAC drug 1200mg twice a day from 24 hours
to be similar in appearance. Intervention 2: Intervention group: In this group, in addition to the items mentioned in the control group, COQ10 supplement (with a dose of 100 mg) will be prescribed dai
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: GFR lower than 60 age upper than 18 years
Exclusion criteria
Exclusion criteria: perform urgent PCI or CAG before receiving standard care 24 hours before receiving contrast presence of liver failure presence of multiple myeloma disease and other plasma cell disorders single kidney patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Contrast nephropathy that occurs if Cr increases and urine volume decreases less than 0.5 cc/kg/h for at least 6 hours will be considered equivalent to acute kidney injury. Timepoint: In both groups, at the beginning and on the third and fifth days, the baseline level of Bun-Cr-GFR and in addition the amount of urine volume will be measured on days 0 and 3. Method of measurement: Blood and urine laboratory tests to check Bun-Cr-GFR and urine volume. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactParham Porteghali
Rasht University of Medical Sciences
Outcome results
None listed