Effect of myo-inositol on PCOS

Effect of myo-inositol on the expression of survivin and caspase 3&7 genes in granulosa cells and the level of biochemical factors of follicular fluid and its relation on oocytes and embryos quality in patients with PCOs undergoing ICSI treatment

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220921056008N1

Enrollment

Registered

2022-10-19

Start date

2022-05-22

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome.

Interventions

Intervention 1: Intervention group:This group includes 30 patients with polycystic ovary syndrome who were candidates for infertility treatment with ICSI according to the opinion of the gynecologist.

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: PCOS diagnostic criteria based on the Rotterdam consensus

Exclusion criteria

Exclusion criteria: Male factor infertility. Cushing syndrome. Congenital adrenal hyperplasia. Thyroid dysfunction, hyperprolactinemia, androgen secretion neoplasia, diabetes mellitus

Design outcomes

Primary

Measure	Time frame
The level of gene expression of caspase 3 and 7 and survivin. Timepoint: After ovarian puncture. Method of measurement: Real time PCR.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeynab Yazdanpanah

Islamic Azad University

zyazdanpanah@piau.ac.ir+98 25 3760 8379

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026