The effect of using sweet-tasting solutions on pain perception caused by dental anesthesia injections in children

The effect of administrating a sweet-tasting solution (30% Sucrose solution) in comparison to distilled water on pain perception caused by dental anesthesia injections in children aged of 6-10 years old: a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220917055974N1

Enrollment

Registered

2022-10-28

Start date

2022-09-29

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries with pulp exposure. Dental caries

Interventions

Intervention 1: Intervention group: Sucrose solution 30%, chemical formula C12H22O11, produced by Millipore Sigma, in the amount of 20 ml, is kept in the mouth for one minute before injection and then

Eligibility

Sex/Gender

All

Age

6 Years to 10 Years

Inclusion criteria

Inclusion criteria: Children 6 to 10 years old Having at least one mandibular primary molar that needs pulp therapy Willingness and permission of parents to participate in the study

Exclusion criteria

Exclusion criteria: Dental emergencies such as traumatic dental injuries or tooth pain Non-cooperation of children Allergy to lidocaine or sweet substances such as sucrose Existence of previous anesthesia experience Presence of abscess, redness, and fistula at the injection site Presence of systemic medical conditions (ASA class I or II) History of hospitalization History of previous dental treatment History of mental or anxiety disorders

Design outcomes

Primary

Measure	Time frame
Visual analogue scale grade. Timepoint: Visual analog scale score measurement immediately after the intervention. Method of measurement: Visual analog scale: a spectrum with 10 numbers and schematic images next to the numbers, in which the patient expresses the amount of pain caused by the injection that he has experienced with the help of these numbers, and the greater the pain, the closer the number will be to 10.;Sound, eye, body movement grade. Timepoint: Measure the score of sound, eye, body movement, immediately after the intervention. Method of measurement: sound, eye, body movement grade: a pain measurement tool that measures pain intensity based on three characteristics of sound, eye movements and body movement. The amount of pain shows a number between 0 and 9, which we consider 3 points for each characteristic.	—

Measure

Time frame

Visual analogue scale grade. Timepoint: Visual analog scale score measurement immediately after the intervention. Method of measurement: Visual analog scale: a spectrum with 10 numbers and schematic images next to the numbers, in which the patient expresses the amount of pain caused by the injection that he has experienced with the help of these numbers, and the greater the pain, the closer the number will be to 10.;Sound, eye, body movement grade. Timepoint: Measure the score of sound, eye, body movement, immediately after the intervention. Method of measurement: sound, eye, body movement grade: a pain measurement tool that measures pain intensity based on three characteristics of sound, eye movements and body movement. The amount of pain shows a number between 0 and 9, which we consider 3 points for each characteristic.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactElahe Darvishi

Tehran University of Medical Sciences

elahedarvishi467@yahoo.com+98 21 6621 2744

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026