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Metronidazole and Probiotics in functional flatulence patients

Investigating the therapeutic effect of Probiotics along with Metronidazole and Probiotics alone in patients with functional flatulence

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220916055971N1
Enrollment
45
Registered
2023-03-22
Start date
2023-05-05
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal Bloating. Flatulence

Interventions

Intervention 1: Intervention group 1: At first, for 2 weeks, they will receive 500 mg Metronidazole Tablet of Pars Daru three times a day, and after 2 weeks, they will receive 500 mg FamiLact Probioti

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age between 20 and 50 years Having functional abdominal distention according to the Rome III criteria The first experience of bloating is more than 6 months before the study Abdominal bloating feeling at least 3 days a month in the last 3 months Consent to participate in the study

Exclusion criteria

Exclusion criteria: Any history of chronic inflammatory disease or structural disease of the gastrointestinal tract Any serious physical problem or disease such as inflammation or malignancy ?Abnormal laboratory data Use of Calcium Channel Blocker drugs in the last 3 months Severe stress in the last 6 months Positive family history for colon cancer Pregnancy or breastfeeding\

Design outcomes

Primary

MeasureTime frame
Abdominal Bloadting. Timepoint: Before the start of the study, 2 weeks after the start of the study, 4 weeks after the start of the study, 6 weeks after the start of the study and 8 weeks after the start of the study. Method of measurement: Questionnaire for bloating and IBS-QOL questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Maryam Soheilipour

Esfahan University of Medical Sciences

maryamsoheilip@med.mui.ac.ir0983136201991

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026