The effect of Ibuprofen and Meloxicam on dental anesthesia

Comparison of Premedication Using Ibuprofen and Meloxicam on the success rate of Inferior Alveolar Nerve Block in mandibular first molars with symptomatic Irreversible Pulpitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220909055923N1

Enrollment

165

Registered

2022-09-10

Start date

2022-09-10

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries. Dental caries

Interventions

Intervention 1: Intervention group 1: Ibuprofen capsule 800 mg (Reha Pharmaceuticals) will be used one hour before root canal treatment. Before starting the treatment, their pain level is recorded. On

Eligibility

Sex/Gender

All

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Systemically healthy A history of spontaneous, or severe pain during cold testing Age 20-40 years

Exclusion criteria

Exclusion criteria: Suffering from systemic diseases Allergy to one of the following: Lidocaine, Epinephrine, NSAIDs, Dexamethasone, Caffeine Suffering from asthma, coagulation disorder, nervous and mental disorder, diseases of immune system defects Pregnancy and breastfeeding for women Allergy to the anesthetic Having a heart pace-maker

Design outcomes

Primary

Measure	Time frame
The amount of pain. Timepoint: Before and during root canal treatment. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Forough Reyhani

Tabriz University of Medical Sciences

moh_reyhani@yahoo.com+98 44 3344 4598

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026