Effect of Supplementation in Polycystic Ovary Syndrome Patients

Assessment of the Effects of Spirulina Supplementation on Metabolic Factors in Polycystic Ovary Syndrome Patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220909055921N1

Enrollment

Registered

2023-10-23

Start date

2023-10-28

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovarian syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: Spirulina, 500 mg capsules, four times a day (morning, noon, evening, night), for 84 days. Intervention 2: Control group: placebo.

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Patients with polycystic ovary syndrome according to the Rotterdam criteria Age range from 18 to 45 years Not following a special diet Not addicted to alcohol or drug abuse The patient should not be pregnant or breastfeeding

Exclusion criteria

Exclusion criteria: History of oophorectomy Use of antidepressants Use of weight loss or appetite suppressants

Design outcomes

Primary

Measure	Time frame
Serum High-Density Lipoprotein. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Enzymatic method using Autoanalyzer.;Total Serum Cholesterol. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Enzymatic method using Autoanalyzer.;Fasting Blood Sugar. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Elisa Kit.;Total Serum Triglyceride. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Enzymatic method using Autoanalyzer.;Serum Low-density Lipoprotein. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Enzymatic method using Autoanalyzer.;Serum Insulin. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Microunits per Milliliter,Enzyme immunoassay test(ELISA).;HemoglobinA1C. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: High Performance Liquid Chromatography with Ion Exchange.	—

Measure

Time frame

Serum High-Density Lipoprotein. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Enzymatic method using Autoanalyzer.;Total Serum Cholesterol. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Enzymatic method using Autoanalyzer.;Fasting Blood Sugar. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Elisa Kit.;Total Serum Triglyceride. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Enzymatic method using Autoanalyzer.;Serum Low-density Lipoprotein. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Enzymatic method using Autoanalyzer.;Serum Insulin. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Microunits per Milliliter,Enzyme immunoassay test(ELISA).;HemoglobinA1C. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: High Performance Liquid Chromatography with Ion Exchange.

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Secondary

Measure	Time frame
Insulin Resistance Index. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Formula.;Blood Pressure. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: mmHg, Barometer.;Weight. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Kilogram-Scale.;Body Mass Index. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Kilogram/Square meter, Calculation (Weight/Height Square).;Waist. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Meter.	—

Measure

Time frame

Insulin Resistance Index. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Formula.;Blood Pressure. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: mmHg, Barometer.;Weight. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Kilogram-Scale.;Body Mass Index. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Kilogram/Square meter, Calculation (Weight/Height Square).;Waist. Timepoint: The first day of the study and the last day of the 12th week. Method of measurement: Meter.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactRezvan Mohammadi

Islamic Azad University

Rezvan.mohamadi72@gmail.com+98 21 2273 5601

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026