Coronary Artery Disease. Atherosclerotic heart disease of native coronary artery
Conditions
Interventions
Intervention 1: Intervention group: After conducting an interview and taking history and medical and medical records, 6 cc of blood was taken from the patient and after centrifugation and serum separa
Sponsors
Semnan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: patients over 30 years old and under 80 years old patients needing CABG surgery Informed consent
Exclusion criteria
Exclusion criteria: patients should have contraindications to colchicine or atorvastatin patients with a history of severe liver diseases patients who have creatinine clearance less than 50. patients with a history of atrial fibrillation or atrial flutter or 2nd and 3rd-degree heart block patients with autoimmune diseases or a history of taking immunosuppressive drugs in the last 1 month patients with heart failure Ejection Fraction < 35% patients with a history of muscle conflicts patients of taking fibrate drugs patients with leukopenia or active infection patients with acute coronary syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interleukin 6. Timepoint: Before and after the intervention. Method of measurement: ELISA method.;CRP. Timepoint: Before and after the intervention. Method of measurement: Spectrophotometry.;LDH. Timepoint: Before and after the intervention. Method of measurement: Spectrophotometry.;ESR. Timepoint: Before and after the intervention. Method of measurement: Spectrophotometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| AF rhythm occurrence. Timepoint: Before and after the intervention. Method of measurement: Electrocardiogram(¬ECG).;Gastrointestinal side effects (nausea, heartache, diarrhea and vomiting). Timepoint: after the intervention. Method of measurement: Examination.;Death. Timepoint: after the intervention. Method of measurement: Examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyedeh Zahra Banihashemian
Semnan University of Medical Sciences
Outcome results
None listed