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Comparing the depth of embryo transfer and its effect on the outcomes of frozen embryo transfer cycles in infertile women applying for frozen embryo transfer

Comparing the depth of embryo transfer and its effect on the outcomes of frozen embryo transfer cycles: a double-blind RCT

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220906055898N2
Enrollment
204
Registered
2022-10-23
Start date
2022-10-11
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intervention group: All patients, with or without suppuration, receive estradiol orally at a dose of 4-6 mg from the second or third day of the menstrual cycle, and after transvaginal

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: • Candidate patients for embryo transfer between 20 and 45 years old • Patients with at least two good quality embryos for transfer • Patients with normal BMI • Patients with a healthy uterine cavity confirmed by hysterosalpingograph and hysteroscope or ultrasound.

Exclusion criteria

Exclusion criteria: • Patients with uncontrolled chronic disease • Patients with donated eggs or embryos • Patients with surrogacy • Poor responder • Patients with endometriosis problems • Non-use or irregular use of medicines • Patients with a history of more than three unsuccessful transplants (RIF) • Presence of hydrosalpinx • Patients with endometrial thickness less than 7 mm after HRT • Patients with adenomyosis • Patients whose embryos are the result of TESE or severe male factor • PGD candidate patients

Design outcomes

Primary

MeasureTime frame
Biochemical pregnancy rates. Timepoint: 2 weeks and 6 weeks after embryo transfer. Method of measurement: Through B-HCG test and transvaginal ultrasound.;Clinical pregnancy rate. Timepoint: 2 weeks and 6 weeks after embryo transfer. Method of measurement: Through B-HCG test and transvaginal ultrasound.

Secondary

MeasureTime frame
Pregnancy. Timepoint: 2 weeks after embryo transfer. Method of measurement: By transvaginl sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmeneh Keshavarzi

Shiraz University of Medical Sciences

s.kharati@yahoo.com+98 71 3230 5410

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026