Alopecia Areata. Alopecia areata
Conditions
Interventions
Patients in group A will receive tofacitinib at 5mg twice daily for 6 months and patients in group B will receive azathioprine in an oral dose of 1-2 mg/kg/day for 6 months.
Sponsors
Lady Reading Hospital Peshawar Pakistan
Eligibility
Sex/Gender
All
Age
12 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients having Alopecia areata with =50% scalp hair loss, Alopecia totalis and Alopecia universalis. Patients must not have received any treatments for Alopecia areata within 2 months of enrollment and will not permitted to use any other treatment known to affect AA Stable or worsening disease for =6 months
Exclusion criteria
Exclusion criteria: Active malignancy or a history of malignancy Leukopenia, Anemia Hepatic or renal impairment Human immunodeficiency virus, Hepatitis B and C. Pregnant or nursing women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of Alopecia Tool (SALT) score. Treatment will be considered efficacious if percent change in SALT score is > 50%. Timepoint: before intervention and 3 months and 6 months after intervention. Method of measurement: Severity of Alopecia Tool (SALT) score. | — |
Countries
Pakistan
Contacts
Public ContactFarah Sagheer
Lady Reading Hospital Peshawar Pakistan
Outcome results
None listed