The Effects of gain versus loss messages following adherence to the DASH diet and a low glycemic index diet in multiple sclerosis

The Effects of gain-versus-loss messages following adherence to the Dietary Approaches to Stop Hypertension (DASH) diet and a low-glycemic index diet on stress, anxiety, depression and fatigue in multiple sclerosis patients: a randomized controlled clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220902055853N3

Enrollment

Registered

2023-10-21

Start date

2023-09-11

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis. Multiple sclerosis

Interventions

Intervention 1: Intervention group 1: The gain-framed health messages refer to a DASH diet and low glycemic index with a positive capacity for 12 weeks. Intervention 2: Intervention group2: The loss-f

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Having multiple sclerosis Age range of 18 to 55 years Stable in disease-modifying treatment for 6 months No relapse in the last 30 days Willing to participate in project (filling informed consent form) Access through Computer or smartphone to the Internet Extended Disability Status Scale (EDSS) less than 4.5 Literate people

Exclusion criteria

Exclusion criteria: Suffering from other types of multiple sclerosis, , if ,, , in the study Suffering from any other neurological disease Simultaneously participating in another study Taking insulin , menopause, history of kidney stones in the last 5 years Illiterate or unwilling to read Unwillingness to continue participation

Design outcomes

Primary

Measure	Time frame
Fatigue. Timepoint: At the beginning and end of study. Method of measurement: Using Modified Fatigue Impact Scale (MFIS) questionnaire.	—

Secondary

Measure	Time frame
Stress. Timepoint: At the begin and end of study. Method of measurement: Using the Depression Anxiety Stress Scale-21 Items (DASS-21) questionnaire.;Anxiety. Timepoint: At the begin and end of study. Method of measurement: Using the Depression Anxiety Stress Scale-21 Items (DASS-21) questionnaire.;Depression. Timepoint: At the begin and end of study. Method of measurement: Using the Depression Anxiety Stress Scale-21 Items (DASS-21) questionnaire.;Physical Activity. Timepoint: At the begin and end of study. Method of measurement: Short form of the International Physical Activity Questionnaire (IPAQ-SF).;Dietary intake (Energy, Carbohydrate, Fat, Protein). Timepoint: At the begin and end of study. Method of measurement: Using Nutritionist IV software.;Intensity of pain. Timepoint: At the begin and end of study. Method of measurement: using the visual analog scale (VAS) questionnaire.	—

Measure

Time frame

Stress. Timepoint: At the begin and end of study. Method of measurement: Using the Depression Anxiety Stress Scale-21 Items (DASS-21) questionnaire.;Anxiety. Timepoint: At the begin and end of study. Method of measurement: Using the Depression Anxiety Stress Scale-21 Items (DASS-21) questionnaire.;Depression. Timepoint: At the begin and end of study. Method of measurement: Using the Depression Anxiety Stress Scale-21 Items (DASS-21) questionnaire.;Physical Activity. Timepoint: At the begin and end of study. Method of measurement: Short form of the International Physical Activity Questionnaire (IPAQ-SF).;Dietary intake (Energy, Carbohydrate, Fat, Protein). Timepoint: At the begin and end of study. Method of measurement: Using Nutritionist IV software.;Intensity of pain. Timepoint: At the begin and end of study. Method of measurement: using the visual analog scale (VAS) questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaezeh Moeini Badi

Ahvaz University of Medical Sciences

moeinibadifaezeh@gmail.com+98 61 3336 2414

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026