Type 2 diabetes. Diabetes mellitus due to underlying condition
Conditions
Interventions
Intervention 1: Intervention group: Co-supplementation of Curcumin + Amla (curcumin 250 mg and Amla 250 mg, 2 capsules of 500 mg daily) half an hour after main meals for period of 12 weeks. Intervent
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: Individuals who are diagnosed with T2DM for at least one years ago Age range from 25 to 65 years BMI range between 25 to 34.9 kg/m2 Taking oral blood sugar lowering drugs to control diabetes Consent to participate in the study
Exclusion criteria
Exclusion criteria: Having chronic diseases (liver, kidney, heart, thyroid, rheumatic, pulmonary, metabolic, digestive, malignancies, allergies) Pregnancy lactation Insulin treatment Taking food supplement, vitamin and mineral for at least in the last 3 months Taking other medicinal plants routinely for at least in the last 3 months Having a weight loss diet for at least in the last6 months Smoking Taking drugs or alcohol in the last 6 months Taking steroid anti-inflammatory drugs and fiber supplements Participate in another trial at the same time
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood glucose. Timepoint: At the beginning and end of study. Method of measurement: Serum sample.;Hemoglobin A1c. Timepoint: At the beginning and end of study. Method of measurement: Serum sample.;Fasting Insulin. Timepoint: At the beginning and end of study. Method of measurement: Serum sample.;Hs Crp. Timepoint: At the beginning and end of study. Method of measurement: Sample serum.;Insulin Sensitivity. Timepoint: At the beginning and end of study. Method of measurement: Formula based.;Insulin resistance. Timepoint: Aat the beginning and end of study. Method of measurement: Formula based. | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic and Diastolic Blood Pressure. Timepoint: At the beginning,and end of the study. Method of measurement: mercury sphygmomanometer.;Dietary intake (Energy, Carbohydrate, Fat, Protein). Timepoint: At the beginning, and end of the study. Method of measurement: Using Nutritionist IV software.;Physical Activity. Timepoint: At the beginning,and end of the study. Method of measurement: Short form of the International Physical Activity Questionnaire (IPAQ-SF).;Health-related Quality of life. Timepoint: At the beginning, and end of the study. Method of measurement: SF-12 questionnaire.;Serum triglyceride. Timepoint: At the begin and end of study. Method of measurement: Serum sample.;Total cholesterol. Timepoint: At the begin and end of study. Method of measurement: Serum sample.;Serum Low Density lipoprotein -Cholesterol (LDL-C). Timepoint: At the begin and end of study. Method of measurement: Serum sample.;Serum high Density lipoprotein -Cholesterol (HDL-C). Timepoint: At the begin and end of study. Method of measurement: Serum sample.;Malondialdehyde (MDA. Timepoint: At the begin and end of study. Method of measurement: Serum sample.;Total Antioxidant Capacity (TAC). Timepoint: At the begin and end of study. Method of measurement: Serum sample.;Superoxide dismutase (SOD). Timepoint: At the begin and end of study. Method of measurement: Serum sample.;Aspartate Transaminase (AST). Timepoint: At the begin and end of study. Method of measurement: Serum sample.;Alanine Transaminase (ALT). Timepoint: At the begin and end of study. Method of measurement: Serum sample.;Gamma-Glutamyl Transferase (GGT). Timepoint: At the begin and end of study. Method of measurement: Serum sample.;Body mass index. Timepoint: At the begin and end of study. Method of measurement: Height and weight measurement with scale with the accuracy of 0.1and apply it in the BMI formula. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Behrouzi
Ahvaz University of Medical Sciences
Outcome results
None listed