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Effect of high-intensity interval training on obesity

The effect of high-intensity interval training and beta-alanine supplementation on the basal levels and acute exercise response of oxidative-inflammatory markers in overweight/obese men

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220828055811N1
Enrollment
28
Registered
2022-10-10
Start date
2022-10-22
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity. Overweight and obesity

Interventions

Intervention 1: First intervention group: Consumption of beta-alanine supplement from My Protein company for six weeks in the amount of 6.4 grams daily in the form of 8 capsules of 0.8 grams (two caps

Sponsors

The University of Shahid Beheshti
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Men Body mass index from 25 to 35 kilogram per square meter All persons with at least 25 percent body fat Inactive Age 18 to 35 years

Exclusion criteria

Exclusion criteria: Smoking Having an underlying disease Blood Glucose above 110 mg per liter; Hematocrit below 35% Hemoglobin below 13 g/dl WBC count more than 11,000 per microliter

Design outcomes

Primary

MeasureTime frame
Serum tumor necrosis factor alpha (TNFa). Timepoint: At the beginning of the study, six weeks after the start of the supplement and exercises and 30 minutes after the end of the last training session. Method of measurement: Using ELISA method and kit made in Germany (LDN company).;Serum high-sensitivity C-reactive protein (hs-CRP). Timepoint: At the beginning of the study, six weeks after the start of the supplement and exercises and 30 minutes after the end of the last training session. Method of measurement: Using ELISA method and kit made in Germany (LDN company).;Serum interleukin 10. Timepoint: At the beginning of the study, six weeks after the start of the supplement and exercises and 30 minutes after the end of the last training session. Method of measurement: Using ELISA method and kit made in Germany (LDN company).;Serum Malondialdehyde (MDA). Timepoint: At the beginning of the study, six weeks after the start of the supplement and exercises and 30 minutes after the end of the last training session. Method of measurement: Using Fluorometric method and kit made in Iran (KPG company).;Serum total antioxidant capacity. Timepoint: At the beginning of the study, six weeks after the start of the supplement and exercises and 30 minutes after the end of the last training session. Method of measurement: Using Fluorometric method and kit made in Iran (KPG company).

Secondary

MeasureTime frame
Body Composition. Timepoint: At the beginning of the study and six weeks after the start of the supplement and training. Method of measurement: Using inbody 770 machine.;High Density Lipoprotein (HDL). Timepoint: At the beginning of the study and six weeks after the start of the supplement and training. Method of measurement: Using Hitachi 717 machine and kit made in Iran.;Low Density Lipoprotein (LDL). Timepoint: At the beginning of the study and six weeks after the start of the supplement and training. Method of measurement: Using Hitachi 717 machine and kit made in Iran.;Triglyceride (TG). Timepoint: At the beginning of the study and six weeks after the start of the supplement and training. Method of measurement: Using Hitachi 717 machine and kit made in Iran.;Cholesterol. Timepoint: At the beginning of the study and six weeks after the start of the supplement and training. Method of measurement: Using Hitachi 717 machine and kit made in Iran.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamad Saber Ebrahimi Zarandi

The University of Shahid Beheshti

m.ebrahimizarandi@mail.sbu.ac.ir+98 21 2990 5824

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026