Investigation of Rocaltrol prescribed before parathyroidectomy surgery to assess the effect of hypocalcemia after surgery in patients with parathyroid edenoma

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220822055773N2

Enrollment

Registered

2022-09-03

Start date

2016-07-22

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Investigation of Rocaltrol prescribed before parathyroidectomy surgery to assess the effect of hypocalcemia after surgery in patients with parathyroid edenoma. Primary hyperparathyroidism

Interventions

Intervention 1: The study population is all primary hyperparathyroidism patients who underwent surgery in the surgery department of Shariati Hospital. For all patients before surgery, the level of PTH

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Primary hyperparathyroidism patients operated in the surgery department of Shariati Hospital

Exclusion criteria

Exclusion criteria: Patients who have hyperparathyroid crisis before the operation and those who are going to remove all 4 parathyroid glands (patients with MEN) are excluded from the study.

Design outcomes

Primary

Measure	Time frame
The use of oral rocartrol before surgery to reduce hypocalcemic symptoms and reduce the need for hospitalization in primary hyperparathyroidism patients. Timepoint: PTH measurement during surgery and before incision and 10 minutes after adenoma removal - serum calcium measurement every 6 hours after surgery. Method of measurement: Demographic information is obtained by interviewing the patient. From the results of the laboratory, data related to the measurement of calcium, PTH, Vit D, Alk.p, through ultrasound or scanning of the adenoma site and through clinical examination of hypocalcemic symptoms are extracted.	—

Measure

Time frame

The use of oral rocartrol before surgery to reduce hypocalcemic symptoms and reduce the need for hospitalization in primary hyperparathyroidism patients. Timepoint: PTH measurement during surgery and before incision and 10 minutes after adenoma removal - serum calcium measurement every 6 hours after surgery. Method of measurement: Demographic information is obtained by interviewing the patient. From the results of the laboratory, data related to the measurement of calcium, PTH, Vit D, Alk.p, through ultrasound or scanning of the adenoma site and through clinical examination of hypocalcemic symptoms are extracted.

—

Secondary

Measure	Time frame
PTH measurement during surgery and before incision and 10 minutes after adenoma removal - serum calcium measurement every 6 hours after surgery. Timepoint: PTH measurement during surgery and before incision and 10 minutes after adenoma removal - serum calcium measurement every 6 hours after surgery. Method of measurement: Demographic information is obtained by interviewing the patient. From the results of the laboratory, data related to the measurement of calcium, PTH, Vit D, Alk.p, through ultrasound or scanning of the adenoma site and through clinical examination of hypocalcemic symptoms are extracted.	—

Measure

Time frame

PTH measurement during surgery and before incision and 10 minutes after adenoma removal - serum calcium measurement every 6 hours after surgery. Timepoint: PTH measurement during surgery and before incision and 10 minutes after adenoma removal - serum calcium measurement every 6 hours after surgery. Method of measurement: Demographic information is obtained by interviewing the patient. From the results of the laboratory, data related to the measurement of calcium, PTH, Vit D, Alk.p, through ultrasound or scanning of the adenoma site and through clinical examination of hypocalcemic symptoms are extracted.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShirzad Nasiri Zaviki

Tehran University of Medical Sciences

Dr.sh.nasiri@gmail.com+98 21 8863 3039

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026