Comparison of the therapeutic effect of metformin and insulin in diabete

Comparison of Pregnancy outcomes in women with gestational diabetes treated with metformin and insulin

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220817055738N1

Enrollment

100

Registered

2022-10-04

Start date

2020-09-22

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational diabetes mellitus. Diabetes mellitus arising in pregnancy

Interventions

Intervention 1: Intervention group 1: In the insulin group, if the fasting blood glucose was high, NPH insulin was prescribed at the rate of 0.2 units per kilogram before going to bed. If the postpran

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Fasting blood glucose (92-125 mg/dl),, 1-hour blood glucose = 180 mg/dl after 75 grams of oral glucose 2-hour blood glucose (153-199 mg/dl) after 75 grams of oral glucose

Exclusion criteria

Exclusion criteria: Women for whom metformin is contraindicated Diagnosed fetal anomaly Rupture of the fetal membrane at the time of entering the study Presence of any other medical condition

Design outcomes

Primary

Measure	Time frame
Blood sugar level. Timepoint: Fasting blood sugar and postprandial blood sugar of the participants were monitored weekly. A comparison of the blood sugar level measured with a glucometer and plasma blood sugar was made to check the accuracy of the stated blood sugar level. Method of measurement: Glucometer and plasma blood sugar.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGolshan Noorollahi

Shahid Beheshti University of Medical Sciences

gnurollahiii@gmail.com+98 45 3379 0310

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026