Endometriosis. Endometriosis, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age group 18-35 years old • No menopause • Definitive diagnosis of endometriosis in the last 10 years • Experience of moderate to severe pain (pain score 6-7) • Patients who have resisted common endometriosis treatments or did not respond well to previous treatments. • Written patient consent.
Exclusion criteria
Exclusion criteria: history of chronic pelvic pain that was not due to endometriosis. History of autoimmune, cardiovascular and kidney diseases according to the patient. Abnormal liver enzymes. History of osteoporosis according to the patient. History of other metabolic diseases, including diabetes, dyslipidemia, and metabolic syndrome according to his tests • Simultaneous reception of steroid hormones in different pharmaceutical forms and various doses in the last 3 months • Simultaneous reception of GnRH analogs in the last 3 months • Simultaneous reception of systemic glucocorticoids in the last 3 months • Lack of patient satisfaction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intensity of pain. Timepoint: Before and 12 weeks after treatment. Method of measurement: Vas score questionnaire.;Interleukin-6. Timepoint: Before and 12 weeks after treatment. Method of measurement: ELISA reader device.;TNFa. Timepoint: Before and 12 weeks after treatment. Method of measurement: ELISA reader device.;Abdominal and pelvic ultrasound findings. Timepoint: Before and 12 weeks after treatment. Method of measurement: Ultrasound device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Islamic Azad University