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The effect of alpha lipoic acid on pain and expression of genes involved in implantation in infertile women with endometriosis

The effect of alpha lipoic acid on pain and expression of genes involved in implantation in infertile women with endometriosis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220817055727N1
Enrollment
30
Registered
2022-09-11
Start date
2022-12-21
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis.

Interventions

Intervention group: In this study, people will be treated with alphalipoic acid (600 mg per day) for 8 weeks. After 8 weeks, with the consent of the patient, a biopsy of the patient's endometrium is p

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women aged 18-44 years with pain and suspected endometriosis Do not take hormonal drugs containing estrogen or progesterone for three months No pregnancy Absence of genital or breast cancers No abnormal vaginal bleeding No breastfeeding for 3 months Do not use housing during the last week No surgery in the last 3 months No liver problems No strong history of venous thrombosis or embolism Body mass index 5 / 18-26

Exclusion criteria

Exclusion criteria: Has a history of any genital cancer in the pelvic area Hormone therapy for the past 3 months Suffering from a variety of systemic diseases History of endometrial destruction by thermal balloon or resectoscope

Design outcomes

Primary

MeasureTime frame
Intensity of pain. Timepoint: Before and 8 weeks after treatment. Method of measurement: Vas score questionnaire.;The level of expression of genes involved in implantation. Timepoint: Before and 8 weeks after treatment. Method of measurement: pcr-real time device.

Countries

Iran (Islamic Republic of)

Contacts

Public Contact???? ???? ???????

Iran University of Medical Sciences

shchaichian@gmail.com+98 21 6435 2562

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026