The effect of Arnebia euchchroma and Phenytoin Cream on pain and episiotomy wound healing

Investigating the Effect of Arnebia euchchroma and Phenytoin Cream on pain and episiotomy wound healing in primiparous women

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220816055724N2

Enrollment

120

Registered

2022-10-18

Start date

2022-09-23

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Pain severity. Condition 2: Wound healing. Other chronic postprocedural pain Disruption of perineal obstetric wound

Interventions

Intervention 1: Intervention group: Arnebia euchchroma cream is applied every 8 hours on days 1 to 10 after giving birth to the episiotomy wound after washing the perineum. Intervention 2: Interventi

Eligibility

Sex/Gender

Female

Age

15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Normal pregnancy and delivery Age between 15-45 Primeparous Body mass index (after delivery) between 18.5-30 kilograms per square meter Having at least reading and writing literacy

Exclusion criteria

Exclusion criteria: Gestational age below 37 weeks or above 42 weeks Suffering from diseases that interfere with wound healing (such as anemia, infection and wounds in the perineum, diabetes, blood pressure, skin, heart, kidney, lung diseases, coagulation disorder, immunodeficiency, hemophilia, connective tissue disorder, depression, malnutrition, mental illness, cancer) Taking drugs effective on wound healing by the mother (anticoagulants, antidepressants, antiepileptics), alcohol, smoking, glucocorticoids, immune system suppressors, antibiotics, and narcotics and psychotropic drugs, not doing chemotherapy The duration of rupture of the water bag more than 18 hours Instrumental vaginal delivery with medial or lateral episiotomy incision Non spontaneous removal of the placenta History of injury or previous surgery and visible lesions in the perineum (genital warts, hemorrhoids) and persistent constipation (according to the patient's statement)

Design outcomes

Primary

Measure	Time frame
Pain severity. Timepoint: Days 1, 5 and 15 after delivery. Method of measurement: Using the VAS pain questionnaire and Disposable paper ruler.;Wound healing. Timepoint: Days 1, 5 and 15 after delivery. Method of measurement: Using the Reeda pain questionnaire.	—

Secondary

Measure	Time frame
Drug side effects. Timepoint: Days 1,5,15 after delivery. Method of measurement: Cheek list.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Medie Salehi

Arak University of Medical Sciences

daneshkadeha@arakmu.ac.ir+98 86 3147 3520

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026