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evaluation of the effect of caffeic acid on recurrent aphthous stomatitis improvement

evaluation of the effect of caffeic acid on recurrent aphthous stomatitis improvement

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220815055700N1
Enrollment
50
Registered
2022-09-03
Start date
2022-09-17
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Minor recurrent stomatitis aphthous. K12.0

Interventions

Intervention 1: Intervention group: receiving mucoadhesive tablet which contain Caffeic acid. Intervention 2: Control group: receiving mucoadhesive tablet which not contain any amount of Caffeic acid.

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: being infected to minor stomatitis aphthous type age range 20 to 40 having aphthous ulcer in lips and buccal area of the mouth having sufficient knowledge for understanding the testimonial

Exclusion criteria

Exclusion criteria: being infected to major or herpeti form having aphthous ulcer in other area except lips and buccal having systemic disease using immunosuppressive drugs having denture pregnant disease which having syndromes such as behcet's disease patients who smoke patient who cannot fill their testimonial

Design outcomes

Secondary

MeasureTime frame
Duration of having aphthous. Timepoint: After 7 days. Method of measurement: Visual Analog Scale and dimeter of erythematosus.

Primary

MeasureTime frame
Pain and inflammation. Timepoint: 0 ,3,5 and 7 days after. Method of measurement: Visual analog scale for pain and diameter of erythematosus around aphthous due to in?flammation.

Countries

Iran (Islamic Republic of)

Contacts

Public Contact???? ????? ?????

Mazandaran University of Medical Sciences

salehimaede1165@gmail.com+98 11 3324 0002

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 9, 2026