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Effect of intra coronary morphine in STEMI

Study of the effect of Intra-coronary morphine vs placebo in the treatment of acute ST-segment elevation myocardial infarction

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220814055685N1
Enrollment
110
Registered
2022-12-10
Start date
2022-12-22
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction with ST elevation. ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction

Interventions

Intervention 1: Intervention group: One dose of morphine sulfate hydrochloride with a dose of 5 mg with a single administration slowly over a period of one to two minutes at the beginning of primary P

Sponsors

Ghoum University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age above 18 years Acute myocardial infarction with STEMI patients

Exclusion criteria

Exclusion criteria: Known allergy to morphine hydrochloride Patients with coronary artery bypass grafting Patients with cardiac arrest are resuscitated Mechanical ventilation on arrival Morphine injection in the emergency room Patients with right ventricular stroke Serious failure of liver cells Any cardiac arrythmia

Design outcomes

Primary

MeasureTime frame
Coronary reperfusion. Timepoint: One and Six Day after the intervention. Method of measurement: Trans thoracic echocardiography.

Secondary

MeasureTime frame
Cardiac enzyme(troponin). Timepoint: Every 12 hours during the first 24 hours and then every 12 hours for the next 48 hours. Method of measurement: Blood test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Fakhreddin Hejazi

Ghoum University of Medical Sciences

sf-hejazi@muq.ac.ir+98 25 3612 2000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026