Investigating the effect of PRP and GCSF on infertility

A comparative study of the effect of platelet-rich plasma (PRP) and granulocyte colony-stimulating factor (GCSF) in patients with recurrent implantation failure

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220813055671N1

Enrollment

Registered

2023-01-29

Start date

2023-01-21

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

recurrent implantation failure.

Interventions

Intervention 1: Intervention group 1 GCSF subcutaneous injection of 300 micrograms once. Intervention 2: Intervention group 2 PRP injection in the amount of 2.5 cc once intrauterine.

Eligibility

Sex/Gender

Female

Age

20 Years to 45 Years

Inclusion criteria

Inclusion criteria: at least 3 and at most 10 implantation failure The possibility of receiving enough platelets informed consent age criteria 20to 45

Exclusion criteria

Exclusion criteria: Hematological disorders (leukemia, thrombocytopenia) immunological disorders (antiphospholipid syndrome, thrombophilia) hormonal disorders (diabetes, thyroid, hyperprolactinemia) chromosomal and genetic abnormalities (hereditary or congenital) kidney failure

Design outcomes

Primary

Measure	Time frame
Pregnancy. Timepoint: 12weeks. Method of measurement: A positive answer for each of the factors alone: seeing the pregnancy sac or seeing the fetal heart in ultrasound or positive chemical pregnancy test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElnaz mostajeran

Esfahan University of Medical Sciences

Elnaz.mostajeran88@yahoo.com+98 31 3336 8908

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026