Left ventricular thrombosis following acute myocardial infarction. Thrombosis of atrium, auricular appendage, and ventricle as current complications following acute myocardial infarction
Conditions
Interventions
Intervention 1: Intervention group: Including 52 patients with left ventricular thrombosis after myocardial infarction who will enter the study with personal consent and after completing the informed
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All patients with left ventricular thrombosis within two weeks after acute myocardial infarction, if there is no contraindication to the use of anticoagulants
Exclusion criteria
Exclusion criteria: History of active bleeding, History of coagulation disorders, Contraindications to Apixaban or warfarin (For example, in patients with ESRD), Drug sensitivity to Apixaban or warfarin, Moderate to severe mitral stenosis, Mechanical valve disease, GFR less than 25, If INR is not within the control-normal range, i.e. 2 to 3, Consumption of drugs which interfere with Apixaban (such as amiodarone, antifungal drugs, anti-AIDS drugs, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of thrombosis and bleeding in patients with left ventricular thrombosis after acute myocardial infarction. Timepoint: At the beginning of the study, 3 months after the intervention. Method of measurement: By Echocardiography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Elimination of thrombus or change in size and its organization in the three-month follow-up, reduction of stroke and other thromboembolic events. Timepoint: Three months after the intervention. Method of measurement: By Echocardiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Baharvand
Rasht University of Medical Sciences
Outcome results
None listed