"Efficacy of diuretic therapy with furosemide compared with combined diuretic therapy with furosemide and indapamide in treatment of congestive heart failure"

Evaluation the efficacy of diuretic therapy with furosemide compared with combined diuretic therapy with furosemide and indapamide in treatment of patients with congestive heart failure: A randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220809055644N1

Enrollment

180

Registered

2022-10-12

Start date

2022-08-23

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congestive heart failure. Congestive heart disease

Interventions

Intervention 1: Intervention group: It will include 90 patients with congestive heart failure. In addition to the daily consumption of furosemide 20 mg three times a day, one pill each time, the inter

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: "Suffering from congestive heart failure" " NYHA class of all participants is 2,3, or 4" " Willingness to participate in the study"

Exclusion criteria

Exclusion criteria: "Severe hypokalemia" "Glomerular filtration rate (GFR) less than 15 ml/min" "Suffering from chronic obstructive pulmonary disease(COPD)" "LVEF more than 40 %" "Diastolic dysfunction grade ? and above" "Uric acid above 10 mg/dL"

Design outcomes

Primary

Measure	Time frame
Assessment symptoms of congestion. Timepoint: At the beginning of the study (before the start of the intervention), one month and three months after the start of taking the studied diuretics. Method of measurement: Physical examination of the patient in terms of congestion.;Evaluation of electrolyte disorders. Timepoint: Before the intervention, 1 month and 3 months after the intervention. Method of measurement: Blood tests.	—

Measure

Time frame

Assessment symptoms of congestion. Timepoint: At the beginning of the study (before the start of the intervention), one month and three months after the start of taking the studied diuretics. Method of measurement: Physical examination of the patient in terms of congestion.;Evaluation of electrolyte disorders. Timepoint: Before the intervention, 1 month and 3 months after the intervention. Method of measurement: Blood tests.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Aris

Rasht University of Medical Sciences

aris_amir@yahoo.com009833618177

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026