Vitiligo. Vitiligo
Conditions
Interventions
Intervention 1: Control group: The combination of microneedling and fluocinolone
In this group, dermapen cartridge 36 (Dr.Pen brand) microneedling with a thickness of 1.5 mm is performed once a week until Pinpoint Bleeding occurs, and after that the patient uses fluocinolone 0.025
In this group, microneedling is performed only once a week. Before performing the process of all three patches, the lesion site is numbed for 20 minutes after sterilizing with 70% alcohol using lidoca
In this group, microneedling is performed once a week, and immediately after microneedling, 5% FU cream is applied on the surface of the lesion as a thick layer, then the lesion is covered with a clos
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
10 Years to No maximum
Inclusion criteria
Inclusion criteria: All patients with stable vitiligo without new lesions in the previous six months who have read and signed the consent form
Exclusion criteria
Exclusion criteria: Pregnant Women Lactating Mothers Facial lesions, genitalia and wrinkled areas Active koebner phenomenon Having coagulation diseases Patients with active infection Patient with high risk of keloid and previous history of keloid Presence of sensitivity to the study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vitiligo lesions repigmentation. Timepoint: At the beginning of the study; After starting the study every week for three months; Three and six months after completing the study. Method of measurement: The amount of change in the area of the lesion after treatment by examining the photos in color analysis software. | — |
Secondary
| Measure | Time frame |
|---|---|
| G-score. Timepoint: After the beginning of repigmentation every week, every month after the end of the study for up to six months. Method of measurement: Color analysis software.;Repigmentation start time. Timepoint: After starting to study, every week. Method of measurement: Observing the color change through photo analysis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNasrin Kheirkhah
Ahvaz University of Medical Sciences
Outcome results
None listed