Neonatal Hyperbilirubinemia. Neonatal jaundice due to other excessive hemolysis
Conditions
Interventions
Intervention 1: Intervention group: 35 infants are placed in the group receiving vitamin E orally with a dose of 0/5 cc (equivalent to 10 drops) orally once a day, on the first, second and third days
Sponsors
Sanandaj University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 30 Days
Inclusion criteria
Inclusion criteria: Term infants with hyperbilirubinemia admitted to the neonatal department of Besat Sanandaj Hospital in 1401 Gestational age from 37 weeks to 42 weeks and 6 days Birth weight from 2500 Grams to 4000 Grams
Exclusion criteria
Exclusion criteria: Evidence of infection Congenital malformation History of phenobarbital use in mother Hypothyroidism Inappropriate intrauterine growth Oral intolerance Mechanical ventilation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean serum total bilirubin. Timepoint: Serum total bilirubin 24 hours, 48 hours and 72 hours after intervention in two groups. Method of measurement: Taking blood samples from the infants in the study at 24 hours, 48 hours and 72 hours after the intervention by a trained nurse and sending them to the lab.;Mean serum indirect bilirubin. Timepoint: Serum indirect bilirubin 24 hours, 48 hours and 72 hours after intervention in two groups. Method of measurement: Taking blood samples from the infants in the study at 24 hours, 48 hours and 72 hours after the intervention by a trained nurse and sending them to the lab.;The amount of changes in the mean serum total bilirubin. Timepoint: Before the intervention and 24, 48 and 72 hours after the intervention. Method of measurement: Comparing the average total serum bilirubin before the intervention and the average total serum bilirubin obtained 24, 48 and 72 hours after the intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| The average number of hospitalization days of newborns in two groups. Timepoint: Number of hospitalization days 24 hours, 48 hours and 72 hours after intervention in two groups. Method of measurement: Registration the number of hospitalization days of the newborns according to the file by a trained nurse.;The average hours of receiving phototherapy for newborns in two groups. Timepoint: Number of hours receiving phototherapy 24 hours, 48 hours and 72 hours after intervention in two groups. Method of measurement: Registering data of number of hours receiving phototherapy by a trained nurse.;Possible complications of vitamin E drug. Timepoint: 24 hours, 48 hours and 72 hours after the intervention in two groups. Method of measurement: A booklet containing the desired questions related to possible complications (these complications are selected by reviewing the literature) is provided to the mothers of babies and is followed up by a trained nurse. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSirous Hematpour
Sanandaj University of Medical Sciences
Outcome results
None listed