Preparation and clinical trial of Mucoadhesive Polymeric Gel Containing Syzygiumaromaticum, Glycyrrhizaglabra, Punicagranatum L. Extract for Treatment of Oral Aphthae

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220731055591N1

Enrollment

Registered

2022-11-02

Start date

2022-08-13

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral aphthae. Recurrent oral aphthae

Interventions

Intervention 1: Placebo group: 20 patients with oral aphthous, receiving placebo gel , three times a day, after breakfast and lunch and before sleeping at night, for 7 days. Intervention 2: Interventi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with aphthous ulcers with at least 5 years old

Exclusion criteria

Exclusion criteria: patients with immunodeficiency disorders

Design outcomes

Primary

Measure	Time frame
Recurrent oral aphthae with at lest 2 mm diameter. Timepoint: every 1 day. Method of measurement: diameter of oral aphthae (mm).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaramarz Dobakhti

Zanjan University of Medical Sciences

Fdobakhti@zums.ac.ir+98 24 3301 8624

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026