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The effectiveness of bupivacaine on pain relief after unilateral knee arthroplasty

A clinical trial to compare the effectiveness of 0.5% bupivacaine with 0.25% bupivacaine on adductor canal block after unilateral knee arthroplasty

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220731055587N1
Enrollment
48
Registered
2022-07-31
Start date
2022-08-23
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unilateral knee arthroplasty. Unspecified complication of internal orthopedic prosthetic device, implant and graft, initial encounter

Interventions

Intervention 1: Intervention group: The intervention group will receive 0.25% bupivacaine to adductor canal block after unilateral knee arthroplasty. Intervention 2: Control group: The control group w

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Months to No maximum

Inclusion criteria

Inclusion criteria: Patients with ASA I or II, who are candidate for unilateral knee arthroplasty Age over 18 years BMI less than 35

Exclusion criteria

Exclusion criteria: History of neuropathy Having coagulation disorder Drug abuse Having local anesthetics allergies

Design outcomes

Primary

MeasureTime frame
The rate of pain. Timepoint: 3, 6, 12 and 24 hours after intervention. Method of measurement: Visual analogue scale (VAS).;Muscle strength. Timepoint: 12 and 24 hours after intervention. Method of measurement: Maximum voluntary isometric contraction (MVIC).

Secondary

MeasureTime frame
The rate of pain reliever consumption. Timepoint: 24 hours after intervention. Method of measurement: Type and amount of pain reliever consumed by the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHosnieh Esmaeili Namghi

Mashhad University of Medical Sciences

hosnie.esmaili@gmail.com+98 51 3854 3031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026