Condition 1: Hypotension, impaired hemodynamic parameters. Condition 2: Impaired cardiac indexes (heart failure). Hypotension Unspecified systolic (congestive) heart failure
Conditions
Interventions
Different patients are admitted in intensive care units with different severity and etiology. The selection of patients was done based on randomization. according to the design of the study, each pati
GIK cocktail infusion (insuline 15 IU+vial Kcl15% 20 mEq+Dextrose 50% 50ml) and in diabetic patients the same cocktail but Insuline 20 IU will apply. rate of infusion will be 10 ml/h for 12 hours. Car
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients admitted in intensive care units needing cardiovascular drug support due to systemic hypotension (shock) Decreased heart performance
Exclusion criteria
Exclusion criteria: Age below 18 years old Patients who do not participate or discontinue Pregnancy Brest feeding Central nerves system and cerebrovascular disease Anemia Chronic kidney disease Active bleeding Metastatic cancer IV drug user Chronic alcohol user Acute multi organ failure Brain death
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: patient's entrance time to ICU, zero time (before prescription), 1h, 6h and 12h after prescription (during infusion). Method of measurement: non invasive blood pressure - automated monitoring.;Stroke volume. Timepoint: patient's entrance time to ICU, zero time (before prescription), 1h, 6h and 12h after prescription (during infusion). Method of measurement: Ultra sonic cardiac output monitoring (USCOM).;Heart rate. Timepoint: patient's entrance time to ICU, zero time (before prescription), 1h, 6h and 12h after prescription (during infusion). Method of measurement: Monitoring device.;Systemic Vascular Resistance. Timepoint: patient's entrance time to ICU, zero time (before prescription), 1h, 6h and 12h after prescription (during infusion). Method of measurement: Ultra sonic cardiac output monitoring (USCOM). | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac output. Timepoint: Patient's entrance time to ICU, zero time (before prescription), 1h, 6h and 12h after prescription (during infusion). Method of measurement: Ultra sonic cardiac output monitoring (USCOM).;Delivery Oxygen. Timepoint: Patient's entrance time to ICU, zero time (before prescription), 1h, 6h and 12h after prescription (during infusion). Method of measurement: Ultra sonic cardiac output monitoring (USCOM). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Jabbari
Tehran University of Medical Sciences
Outcome results
None listed