Obesity adults. Overweight and obesity
Conditions
Interventions
Intervention 1: Intervention group: Daily 600 mg of NAC supplement prepared by Osvah Pharmaceutical Company of Iran for 6 weeks. Intervention 2: Control group: Daily 600 mg maltodextrin supplement pre
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 60 Years
Inclusion criteria
Inclusion criteria: Obese people with a body mass index greater than or equal to 30 kg/m2.Age over 25 years Non-pregnant and lactating Not suffering from chronic and acute inflammatory, and infectious diseases Not suffering from high blood pressure and vascular diseases Not receiving alcohol and smoking
Exclusion criteria
Exclusion criteria: Receiving weight loss and antioxidant drugs and supplements in the last three months Participating in other clinical trial studies at the same time as the present study. Adherence to weight loss diets during the last three months. History of gastrointestinal or bariatric surgeries.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expression of UCP1 genes. Timepoint: At the end of week 6. Method of measurement: Using PCR (polymerase chain reaction). | — |
Secondary
| Measure | Time frame |
|---|---|
| Expression of didinase type 2 and 3 genes. Timepoint: The end of week 6. Method of measurement: Using PCR (polymerase chain reaction).;Expression of alpha and beta thyroid hormone receptor genes. Timepoint: The end of week 6. Method of measurement: Using PCR (polymerase chain reaction).;Serum level of thyroid hormones (TSH, T3 and T4). Timepoint: At the beginning of the study and at the end of week 6. Method of measurement: Blood sampling and measurement by ELISA method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamid Zand
Shahid Beheshti University of Medical Sciences
Outcome results
None listed