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The effect of the ozonated gel on children's dental plaque

The effect of 20 ppm ozonated gel and 1 % chlorhexidine gel on plaque index and the number of Streptococcus mutans obtained from dental plaque in children aged 6-12 years: A double-blind randomized clinical trial study

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220727055562N1
Enrollment
165
Registered
2022-08-15
Start date
2022-08-13
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries. Dental caries

Interventions

Intervention 1: The first intervention group: O3life 20 ppm ozonated gel is applied twice a day (morning and night) half an hour after meals for 3 weeks using a finger on all dental surfaces. After th

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: Age 6 to 12 years Being healthy in the state of systemic condition No known allergies Consent to participate in the study

Exclusion criteria

Exclusion criteria: History of allergy to chlorhexidine or ozone Antibiotic use in the past few months Children with mental and physical disabilities History of frequent food and drug allergies

Design outcomes

Primary

MeasureTime frame
Plaque index. Timepoint: Once before the start of the intervention and the second time after three weeks (at the end of the intervention). Method of measurement: After people use the detector tablet, the amount of plaque index is calculated and recorded.;Number of Streptococcus mutans bacteria. Timepoint: Once before the start of the intervention and the second time after three weeks (at the end of the intervention). Method of measurement: The dental plaque sample will be removed from all surfaces of the desired tooth using a sterile toothpick and will be transferred to the microbiology laboratory and cultured in the Agar medium. The number of bacterial colonies is counted.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZiya Ebrahim Adhami

Tabriz University of Medical Sciences

adhamipedodontist@gmail.com+98 44 3344 4598

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026