Condition 1: ST-elevation myocardial infarction. Condition 2: Cardiac arrhythmia. ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction Other cardiac arrhythmias
Conditions
Interventions
Intervention 1: Intervention group: STEMI patients who are candidates for PPCI, before PCI, receive 2 grams of colchicine as STAT, and from the second day, 0.5 mg of colchicine will be prescribed ever
Sponsors
Qazvin University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with STEMI that are candidates for PPCI
Exclusion criteria
Exclusion criteria: Patients who previously used Colchicine or Prednisolone for any reason Contraindications of Colchicine, including sensitivity to Colchicine, kidney failure (GFR < 10), liver failure (AST - ALT above 5 times normal) and definite history of serious liver diseases (such as hepatitis, hemochromatosis, Wilson's disease, cirrhosis) Drugs that interact with risk X with colchicine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of cardiac arrhythmia. Timepoint: The first day after the occurrence of STEMI. Method of measurement: Checking the rhythm recorded in the 24-hour monitor of the patient.;Cardiac arrhythmia type in the first 24 hours after PPCI. Timepoint: The first day after the occurrence of STEMI. Method of measurement: Checking the rhythm recorded in the 24-hour monitor of the patient.;Comparison of initial and final TIMI of involved vessels. Timepoint: At the beginning and end of coronary angiography. Method of measurement: Based on the standard specified in Branwald's cardiology book, the division is done. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMajid Hajikarimi
Qazvin University of Medical Sciences
Outcome results
None listed