Assessment of the Results of Inovo Sense Smile and Inovo Sense Style Filler Injections to Correction Nasolabial Folds

Evaluation of the Safety and Effectiveness of Inovo Sense Smile and Inovo Sense Style Intradermal Injectable Gel for Correcting Moderate to Severe Nasolabial Folds

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220723055530N1

Enrollment

Registered

2022-07-27

Start date

2022-07-26

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin aging.

Interventions

Injection of Inovo Sense Smile and Inovo Sense Style Intradermal gel in the nasolabial folds, the products are in the 1 ml prefilled sterilized syringe containing: Inovo Sense Smile:Hyaluronic Acid ge

Lidocaine hydrochloride, 0.3%

Phosphate buffer (pH 7), 1 mlInovo Sense Style:Hyaluronic Acid gel, 23 mg

Phosphate buffer (pH 7), 1 ml.

Eligibility

Sex/Gender

All

Age

30 Years to 65 Years

Inclusion criteria

Inclusion criteria: 30 -65 Years old men and women with moderate to severe nasolabial folds Signing the informed consent form

Exclusion criteria

Exclusion criteria: History of a cosmetic procedure in the lower 2/3 of the face during the last three months Previous allergy to Hyaluronic Acid or Lidocaine Presence of inflammation, active infection, unhealed old wound, and skin lesions in the NLF region People prone to hypertrophic scar formation History of autoimmune or immune deficiency diseases Pregnancy or breastfeeding

Design outcomes

Primary

Measure	Time frame
Severity of nasolabial folds. Timepoint: Before intervention, immediately after that, 2 weeks, and 3 months later. Method of measurement: 5-point photonumeric Allergan scale.	—

Secondary

Measure	Time frame
Depth, area and volume of nasolabial folds. Timepoint: Before the intervention, immediately after that, 2 weeks, and 3 months later. Method of measurement: Visioface camera.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeynab Aryanian

Tehran University of Medical Sciences

zeinabaryanian@gmail.com+98 21 5563 0223

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026