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Comparison of the effects of topical spironolactone solution and topical clindamycin solution on mild to moderate acne vulgaris treatment

Comparison of the effects of topical spironolactone solution and topical clindamycin solution on mild to moderate acne vulgaris treatment in Sina hospital, Hamadan

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220720055503N1
Enrollment
80
Registered
2022-07-22
Start date
2022-07-22
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne Vulgaris. Acne vulgaris

Interventions

Intervention 1: Intervention group: Treatment with 2% spironolactone topical solution made by an experienced pharmacist twice a day for 3 months. Intervention 2: Control group: Treatment with 2% clind

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: People with mild to moderate acne 18 years old and above

Exclusion criteria

Exclusion criteria: Pregnant and lactating women Known hypersensitivity to clindamycin History of using oral isotretinoin, laser or chemical peeling in the last 6 months History of taking oral estrogen compounds in the last 3 months History of using retinoid or antibiotics during the last month History of using antimicrobial soaps or topical peels during the last two weeks Chronic skin diseases such as psoriasis, lichen planus, vitiligo Weakness of the immune system or the use of immunosuppressive drugs

Design outcomes

Primary

MeasureTime frame
Acne Severity. Timepoint: Beginning of trial,1 month,2 months and 3 months after treatment. Method of measurement: Global Acne Grading System.

Secondary

MeasureTime frame
Frequency and type of acne lesions. Timepoint: Beginning of trial,1 month,2 months and 3 months after treatment. Method of measurement: Counting type and number of lesions.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBahareh Ebrahimi

Hamedan University of Medical Sciences

b.ebrahimi.4362@gmail.com+98 81 3827 4192

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026