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effect of Lidocaine , esmolol and ketorolac in pain control when injecting rocuronium

Comparison of pretreatment with Lidocaine , esmolol and ketorolac in pain control when injecting rocuronium

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220719055498N1
Enrollment
176
Registered
2022-08-10
Start date
2022-09-23
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain during Rocuronium injection in general anesthesia induction.

Interventions

Intervention 1: Intervention group 1: group K, 10 mg ketorolac (Exir Iran pharmaceutical company) injection in 2 ml in the left arm and 2 mg of 0.9% Normal Saline simultaneously in the the right arm.

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Elective surgery candidates undergoing general anesthesia ASA class I and II

Exclusion criteria

Exclusion criteria: History of Thrombophlebitis, vascular disease, chronic pain, Diabetes History of burns, and tumors in the hand with the catheter History of addiction or any contraindications for the drugs used in the study Not consenting to participate in the study

Design outcomes

Primary

MeasureTime frame
Visual analog scale pain scores. Timepoint: during and 1 minute after Rocuronium injection. Method of measurement: visual analog scale pain.

Secondary

MeasureTime frame
Mean arterial blood pressure. Timepoint: on entering the operation room, 5 minutes and ten minutes after injection of intervention drugs, at the time of induction and every 10 minutes after induction for 30 minutes. Method of measurement: Sphygmomanometer.;Arterial oxygen saturation. Timepoint: on entering the operation room, 5 minutes and ten minutes after injection of intervention drugs, at the time of induction and every 10 minutes after induction for 30 minutes. Method of measurement: pulse oximetry.;Heart beat. Timepoint: on entering the operation room, 5 minutes and ten minutes after injection of intervention drugs, at the time of induction and every 10 minutes after induction for 30 minutes. Method of measurement: taking Radial pulse for 1 minute.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazanin Hassannejad

Arak University of Medical Sciences

nazaninhasannejad.md@gmail.com+98 31 3777 5374

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026