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Probiotic supplementation in multiple sclerosis

The effects of probiotics in functional abilities of multiple sclerosis patients: a randomized double-blind placebo-control trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220713055465N1
Enrollment
90
Registered
2022-08-30
Start date
2022-08-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis. Multiple sclerosis

Interventions

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Definitive diagnosis of multiple sclerosis based on 2017 MacDonald criteria RRMS Informed consent

Exclusion criteria

Exclusion criteria: Lack of consent to continue the study at any stage The presence of other neurological diseases at the same time as MS Diabetes mellitus (DM) Anemia Other inflammatory diseases Rheumatological diseases Acute and chronic infectious diseases (including urinary tract infection) Discopathy Relapsing of the disease in the last 4 months Receiving pulse coronet during the last 4 months Progressive MS CIS (Clinically isolated syndrome) Literacy level below 12 years and lack of proficiency in Persian language Severe depression and use of antidepressants Alcohol or drug abuse Thyroid disorders Taking drugs that affect fatigue Pregnancy

Design outcomes

Primary

MeasureTime frame
Cognitive Impairment. Timepoint: Baseline and end of treatment period. Method of measurement: Symbol Digit Modalities Test and Paced Auditory Serial Addition Test.;Depression. Timepoint: Baseline and end of treatment period. Method of measurement: Beck's Depression Inventory.;Physical disabilities. Timepoint: Baseline and end of treatment period. Method of measurement: Expanded Disability Status Scale (EDSS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahnaz Talebi

Tabriz University of Medical Sciences

Talebi511@yahoo.com+98 41 3334 0730

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026