Multiple Sclerosis. Multiple sclerosis
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Definitive diagnosis of multiple sclerosis based on 2017 MacDonald criteria RRMS Informed consent
Exclusion criteria
Exclusion criteria: Lack of consent to continue the study at any stage The presence of other neurological diseases at the same time as MS Diabetes mellitus (DM) Anemia Other inflammatory diseases Rheumatological diseases Acute and chronic infectious diseases (including urinary tract infection) Discopathy Relapsing of the disease in the last 4 months Receiving pulse coronet during the last 4 months Progressive MS CIS (Clinically isolated syndrome) Literacy level below 12 years and lack of proficiency in Persian language Severe depression and use of antidepressants Alcohol or drug abuse Thyroid disorders Taking drugs that affect fatigue Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive Impairment. Timepoint: Baseline and end of treatment period. Method of measurement: Symbol Digit Modalities Test and Paced Auditory Serial Addition Test.;Depression. Timepoint: Baseline and end of treatment period. Method of measurement: Beck's Depression Inventory.;Physical disabilities. Timepoint: Baseline and end of treatment period. Method of measurement: Expanded Disability Status Scale (EDSS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Tabriz University of Medical Sciences