Evaluation of N-Acetyl Cysteine mouthwash in preventing the occurrence of chemotherapy-induced oral mucositis

Evaluation of the effectiveness of N-Acetyl Cysteine mouthwash in preventing the occurrence of chemotherapy-induced oral mucositis in cancer patients referred to Imam Khomeini Hospital in Sari

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220712055439N1

Enrollment

Registered

2022-08-03

Start date

2022-07-23

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chemotherapy-induced oral mucositis. Oral mucositis (ulcerative)

Interventions

Intervention 1: Intervention group: The intervention group has 34 people and uses N-acetylcysteine ??mouthwash in the amount of 15 ml twice a day for 30 seconds for 14 days. Intervention 2: Control gr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Cancer patients undergoing chemotherapy for the first time Patients who do not have other systemic diseases

Exclusion criteria

Exclusion criteria: Patients who have other systemic diseases Taking antibiotics, drugs, cigarettes and other mouthwashes

Design outcomes

Primary

Measure	Time frame
Intensity of Mucositis. Timepoint: During the 14 days of the study (from the first day to the fourteenth day after the start of chemotherapy). Method of measurement: The oral diseases specialist performs the examination based on the classification of the oral mucositis index and records the results in the classification.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAnahita Ghorbani

Mazandaran University of Medical Sciences

anahita1802@yahoo.com+98 11 3326 3409

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026