Comparative cefixime and levofloxacin on infections after urinary tract dilatation

A comparative study on the effects of prevention antibiotics cefixime and levofloxacin on infections after urinary tract dilatation in patients with recurrent stenosis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220711055433N2

Enrollment

Registered

2022-10-27

Start date

2021-01-06

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urethral Stricture. Urethral stricture, unspecified

Interventions

Intervention 1: Intervention group: Before and after urethral dilatation, a 500mg tablet of levofloxacin is given for 3 days (one dose before urethral dilatation and two doses after urethral dilatatio

Eligibility

Sex/Gender

Male

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Single urethral stricture and stricture length less than 2 cm Strictures shorter than 1.5 cm in the anterior urethra Age older than 18 years old

Exclusion criteria

Exclusion criteria: Patient refusal of participation History of allergy to levofloxacin and cefixime

Design outcomes

Primary

Measure	Time frame
Urinary tract infections after urethral dilatation. Timepoint: The rate of improvement in urinary tract infection in the first, second and third months after dilatation. Method of measurement: The use of Urine analysis and Urine culture.	—

Secondary

Measure	Time frame
Side effects caused by cefixime or levofloxacin. Timepoint: 72 hours after urethral dilatation. Method of measurement: Medical records.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Abbas Asadpour

Mashhad University of Medical Sciences

Asadpouraa@mums.ac.ir+98 51 3843 2256

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026