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Effects of Diclofenac on Urethral stricture treatment pain

Comparison of Sustained-Released Diclofenac with Placebo on Urethral Dilatation Pain score in two groups called Intervention and Control group, in Urethral Stricture Patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220711055433N1
Enrollment
40
Registered
2022-07-19
Start date
2020-05-23
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urethral Stricture. Urethral stricture

Interventions

Intervention 1: Intervention group: one sustained-release Diclofenac tablet (100mg) Sobhan Darou taken orally 10 hours before urethral dilatation. Intervention 2: Control group: one tablet of Placebo

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: Male gender Older than 20 years old Single urethral stricture and stricture length less than 1.5 cm

Exclusion criteria

Exclusion criteria: Urethral stricture due to Balanitis Xerotica Obliterans History of hepatic, renal or gastric diseases Patient refusal of participation History of NSAID Hypersensitivity

Design outcomes

Primary

MeasureTime frame
Pain during urethral dilatation. Timepoint: Immediately after urethral dilatation. Method of measurement: Based on Visual Analogue Scale.;Pain 1 hour after urethral dilatation. Timepoint: 1 hour after urethral dilatation. Method of measurement: Based on Visual Analogue Scale.

Secondary

MeasureTime frame
The need to take analgesics. Timepoint: 24 hours after urethral dilatation. Method of measurement: Yes or No.;Side effects due to Diclofenac. Timepoint: 24 hours after urethral dilatation. Method of measurement: Yes or No.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Abbas Asadpour

Mashhad University of Medical Sciences

Asadpouraa@mums.ac.ir+98 51 3843 2256

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026