Condition 1: Multiple myeloma. Condition 2: non-Hodgkin lymphoma. Multiple myeloma Other specified and unspecified types of non-Hodgkin lymphoma
Conditions
Interventions
Intervention 1: Intervention group: After hospitalization and before transplantation, the patients are first subjected to the mobilization and release of stem cells for about 7 days through the inject
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
22 Years to 62 Years
Inclusion criteria
Inclusion criteria: Malignant Disease with Indication of HSCT, Transplantation of Peripheral Blood Stem Cells by Autologous Method, Age between 22 and 62 Years, Performing an Exercise Test Under the Supervision of a Cardiologist to Check the Patient's Cardiovascular Condition. Karnofsky Performance (KPS) with Scores Above 90 Suitable Functional Capacity of the Patient for Walking on the Treadmill. No History of Chronic Diseases such as High Blood Pressure, Severe Heart Failure, Respiratory Disease and Allergies, Diabetes, Kidney Failure, and Orthopedic Problems No History of Treatment and Radiotherapy
Exclusion criteria
Exclusion criteria: Hemoglobin Below Eight Micrograms Per Liter Decrease in Platelets Below 50,000 Symptoms of Fever, Neutropenia, Bleeding, Nausea
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| White blood cell count. Timepoint: Before and after transplantation. Method of measurement: Analyzer device, model Hitachi 912 made by Roche, Germany.;Hemoglobin count. Timepoint: Before and after transplantation. Method of measurement: Analyzer device, model Hitachi 912 made by Roche, Germany.;Platelet count. Timepoint: Before and after transplantation. Method of measurement: Analyzer device, model Hitachi 912 made by Roche, Germany. | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of platelet units injected. Timepoint: After transplantation. Method of measurement: Counting the number of platelet units injected.;CD34+ hematopoietic progenitor cells. Timepoint: Before and after transplantation. Method of measurement: flow cytometry (Attune NXT, USA Country). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMasoomeh Kamyabnia
Islamic Azad University
Outcome results
None listed