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dexmedetomidine in colonoscopy

Evaluation of hemodynamic changes of dexmedetomidine in comparison with ketamine in patients undergoing colonoscopy under sedation with propofol

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20220706055402N1
Enrollment
70
Registered
2022-08-01
Start date
2022-07-20
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colonoscopy,sedation. Failed moderate sedation during procedure

Interventions

Intervention 1: The intervention group will use propofol with a dose of 0.5 mg per kg and dexmedetomidine with a dose of 1 mg per kg and at a rate of 0.5 mg per kg per hour manufactured by Daro Farah

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The absence of cardiovascular diseases The absence of kidney or liver failure diseases absence of drug addiction absence of contraindications to the use of dexmedetomidine, propofol people which are classified in class 1 and 2 of the American Society of Anesthesiology (II, I class ASA) are selected.

Exclusion criteria

Exclusion criteria: Unwillingness of the patient to participate in the study intestinal perforation during procedure bleeding of the esophagus or stomach or intestine during the procedure changing the type of procedure during colonoscopy or requiring surgery during the procedure

Design outcomes

Primary

MeasureTime frame
Total amount of Propofol consumed. Timepoint: From start to end of colonoscopy. Method of measurement: Dose of drug.;Level of sedation. Timepoint: From start to end of colonoscopy. Method of measurement: Ramsay Sedation Scale.;Amount of pain. Timepoint: From start to one hour after colonoscopy. Method of measurement: Visual Analogue Scale.;Amount of Nausea and Vomiting. Timepoint: From start to end of colonoscopy. Method of measurement: Visual Analogue Scale.;Time of recovery. Timepoint: From start to end of colonoscopy. Method of measurement: From end of colonoscopy to full consciousness.;Hemodynamic instability. Timepoint: From start to end of colonoscopy. Method of measurement: Amount of Heart rate, mean arterial pressure and blood oxygen saturation changes.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Moftakhar

Ahvaz University of Medical Sciences

moftakhar-f@ajums.ac.ir+98 61 3338 3372

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026