Comparative of the effect of oral isotretinoin and desloratadine with oral isotretinoin in the treatment of moderate to severe acne vulgaris patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220705055374N1

Enrollment

Registered

2022-07-11

Start date

2022-08-23

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris. Acne vulgaris

Interventions

Intervention 1: Intervention group: Treatment with isotretinoin capsule 20 mg once daily after lunch and desloratadine 10 mg tablet at night before sleep for 12 weeks. Intervention 2: Control group: T

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patient with moderate to severe acne

Exclusion criteria

Exclusion criteria: Age<18 years Pregnant and lactating female Systemic disease Concurrent use of other acne therapies Other dermatological condition requiring interfering treatment

Design outcomes

Primary

Measure	Time frame
Number of acne lesions after treatment. Timepoint: At baseline and at weeks 4, 8 and 12 after treatment. Method of measurement: Observe and record in the checklist.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactForough Eftekhari

Hamedan University of Medical Sciences

forough.eftekhari8@gmail.com+98 81 3131 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026