?????? ?????? ??? ??????. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: Routine treatment (OCP pill (preferably Desoceptive) one pill per day for 21 days, then 7 days break and start the next pack again) + melatonin 5 mg/day twice for 12 weeks before going
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Women with PCOs according to the Rotterdam criteria willing to participate in the intervention
Exclusion criteria
Exclusion criteria: systemic disease (such as diabetes mellitus, Cushing's syndrome, congenital adrenal hyperplasia, hyperprolactinemia and hyperthyroidism) pregnancy miscarriage or delivery within the last 6 weeks breastfeeding in the first 6 months use of hormonal drugs in the last month sleep disorders family history of breast and ovarian cancer having the intention of pregnancy need for surgery and other interventions personal request of the patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Menstrual disorders associated with polycystic ovary syndrome (menstrual disorders including amenorrhea, oligomenorrhea, menstrual bleeding according to Higham's chart). Timepoint: 0, 6 weeks, 12 weeks. Method of measurement: Menstrual irregularities, including amenorrhea, oligomenorrhea, by asking the person and the amount of menstrual bleeding based on Higham's chart. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hormonal profile. Timepoint: 0, 12 weeks. Method of measurement: laboratory evaluation.;Ovarian sonographic findings. Timepoint: 0, 12 weeks. Method of measurement: ultrasonography.;Anthropometric parameters. Timepoint: 0, 12 weeks. Method of measurement: Weight with calibrated scales, abdominal circumference in meters, body mass index with weight squared.;Hirsutism. Timepoint: 0, 12 weeks. Method of measurement: clinical evaluation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Abdi
Iran University of Medical Sciences
Outcome results
None listed