Condition 1: Burns. Condition 2: Burns. Condition 3: Burns. Condition 4: Burn. Burn and corrosion of shoulder and upper limb, except wrist and hand Burn and corrosion of wrist and hand Burn and corrosion of lower limb, except ankle and foot Burn and corrosion of ankle and foot
Conditions
Interventions
Intervention 1: Intervention group:Patients with deep 2nd degree burns and treated with Swalin ointment. Intervention 2: Control group: Patients with deep 2nd degree burns and treated with 1% silver s
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 45 Years
Inclusion criteria
Inclusion criteria: Age 15-45 years, 2nd degree thermal burn wound of 1% to 2% depth of the body, less than 24 hours have passed since the burn, good general condition and no pregnancy, no underlying disease such as diabetes, no history of autoimmune diseases, No HIV infection, no immune system deficiency, no history of taking immunosuppressant drugs, no history of psychiatric disorders, no history of electrical chemical thermal burns, no history of allergies and sensitivities.
Exclusion criteria
Exclusion criteria: Other types of burns, such as chemical, electrical, etc., wound stained with polluting substances, using any substance other than drinking water on the wound before entering the study, untreated active infection in different parts of the body, patients with underlying diseases and immune system defects such as cancer, AIDS, diabetes, high blood pressure, etc., burns on the face and genital areas, pregnant and lactating women,
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The size of the burn surface. Timepoint: Days 1, 7, 14, 21 and 28. Method of measurement: Photo image using imageJ software. | — |
Secondary
| Measure | Time frame |
|---|---|
| Angiogenesis factors. Timepoint: fourteenth day. Method of measurement: ELISA assay.;Inflammatory factors. Timepoint: Days 3, 7 and 14. Method of measurement: ELISA assay.;The amount of collagen. Timepoint: fourteenth day. Method of measurement: Masson's Trichrome Stain.;Number of vascular sections. Timepoint: fourteenth day. Method of measurement: H&E Staining.;Epithelialization. Timepoint: fourteenth day. Method of measurement: H&E Staining. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehrdad Bakhtiyari
Iran University of Medical Sciences
Outcome results
None listed