The Effect of a Multi Component Exercise Program on Cognitive Function of Women with Type 2 Diabetes

The Effect of a Multi Component Exercise Program on Cognitive Function in Women with Type 2 Diabetes, with a Special Focus on Serum Levels and Geno typing of Selected cytokine TNF alpha and IL-10 Polymorphisms

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20220702055347N1

Enrollment

100

Registered

2023-06-20

Start date

2023-06-22

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes. Type 2 diabetes mellitus without complications

Interventions

Intervention 1: "Intervention group": A 3-month multi component exercise intervention consisting of stretching, resistance, dual task and balance exercises will be implemented. The intensity of aerobi

Eligibility

Sex/Gender

Female

Age

50 Years to 75 Years

Inclusion criteria

Inclusion criteria: Fasting blood glucose more than 7 mmol/L Hemoglobin A1c more than 6.5 Do not have cognitive function, heart and joint problems People with type 2 diabetes Be in the desired age range

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Interleukin 10 genotyping. Timepoint: Before and after 3 months interventions. Method of measurement: Restriction fragment length polymorphism.;Tumour necrosis factor a genotyping. Timepoint: Before and after 3 months interventions. Method of measurement: Restriction fragment length polymorphism.	—

Secondary

Measure	Time frame
Tumor necrosis factor alpha cytokine. Timepoint: Before and after 3 months intervention. Method of measurement: Enzyme-linked immunosorbent assay.;Interleukin 10 cytokine. Timepoint: Before and after 3 months intervention. Method of measurement: Enzyme-linked immunosorbent assay.;Executive function. Timepoint: Before and after 3 months intervention. Method of measurement: Trail Making Test.;Respiratory and cardiovascular system, blood circulation and muscle. Timepoint: Before and after 3 months intervention. Method of measurement: 6-Minute Walk Test.;Body Mass Index. Timepoint: Before and after 3 months intervention. Method of measurement: Weight in kilograms divided by the square of height in meters.	—

Measure

Time frame

Tumor necrosis factor alpha cytokine. Timepoint: Before and after 3 months intervention. Method of measurement: Enzyme-linked immunosorbent assay.;Interleukin 10 cytokine. Timepoint: Before and after 3 months intervention. Method of measurement: Enzyme-linked immunosorbent assay.;Executive function. Timepoint: Before and after 3 months intervention. Method of measurement: Trail Making Test.;Respiratory and cardiovascular system, blood circulation and muscle. Timepoint: Before and after 3 months intervention. Method of measurement: 6-Minute Walk Test.;Body Mass Index. Timepoint: Before and after 3 months intervention. Method of measurement: Weight in kilograms divided by the square of height in meters.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Mahdieh Molanouri Shamsi

Tarbiat Modares University of Tehran

molanouri@modares.ac.ir+98 21 8288 4683

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026